Slow-release sodium valproate tablets

Details Slow-release sodium valproate tablets Slow-release sodium valproate tablets

1995-06-07

1996-12-31

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424495, 424489, 424471, A61K 936

Patent

active

055891918

ABSTRACT:
A slow, release sodium valproate tablet with a coating layer, obtained by coating a core containing sodium valproate with a coating agent comprising ethyl cellulose having silicic acid anhydride dispersed therein. The slow-release tablets, while having a relatively small size, maintain a stable dissolution rate without being influenced by pH conditions to stably maintain the blood concentration of active agent over an extended period of time.

REFERENCES:
patent: 4684516 (1987-08-01), Bhutani
patent: 5017613 (1991-05-01), Aubert et al.
patent: 5019398 (1991-05-01), Daste
patent: 5055306 (1991-10-01), Barry et al.
patent: 5185159 (1993-02-01), Aubert et al.

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