Slow release pharmaceutical composition

Details Slow release pharmaceutical composition Slow release pharmaceutical composition

1983-10-28

1985-06-18

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

424 20, 424 21, 424 22, 424 38, A61K 928, A61K 952

Patent

active

045240604

ABSTRACT:
The invention provides a sustained release pharmaceutical composition comprising a mixture of micronized indoramin or a pharmaceutically acceptable salt thereof, a water-channelling agent, a wetting agent and a disintegrant, the mixture being in the form of a non-compressed pellet and having an enteric coat or a sustained release coat permeable to gastrointestinal juices. Sustained release capsules are also provided comprising a plurality of the aforementioned pellets.

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Asahi Chem, Chem. Abstr., 88, #141688j (1978) of Japan Kokai 78-09315, 27 Jan. 1978.
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Asahi Chem, Chem. Abstr., 94, #52961z (1981) of Jpn. Kokai 80-122726, 20 Sep. 1980.
Wong et al., Chem. Abstr., 96, #57787y (1982) of U.S. 4,304,773.
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Kornblum et al., (I) J. Pharm. Sci., 62(1): 43-49, Jan. 1973, New Tablet Disintegrating Agent: Cross-Linked Polyvinylpyrrolidone.

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