Slow-release pharmaceutical agent

Details Slow-release pharmaceutical agent Slow-release pharmaceutical agent

1986-09-15

1993-02-23

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424471, 424472, A61K 922

Patent

active

051888408

ABSTRACT:
A slow-release pharmaceutical agent which comprises fumaric acid and/or DL-tryptophan in addition to one or more pharmaceutically active substances, and a process for preparation of the same are disclosed. Among many organic acids and amino acids, fumaric acid and DL-tryptophan are remarkably useful for extending the duration of release of a pharmacologically active substance when fumaric acid, DL-tryptophan or both is used for formulation of a pharmaceutical agent. The pharmaceutical agent may be in any solid form of formulations such as powder, granule, tablet, troche, capsule, suppository, etc., and may be used with practically all types of drugs.

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Remington's Pharmaceutical Sciences Treatise, 17th Edition (1985), pp. 1603-1604.

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