Slow-onset, long-lasting dopamine reuptake blockers

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 31135

Patent

active

060110708

ABSTRACT:
Disclosed is a method of treating an individual who abuses cocaine by administering to the individual a therapeutically effective amount of an N,N-dialkyl 3-phenyl-1-indanamine or a mixture of N,N-dialkyl 3-phenyl-1-indanamines. Also disclosed is a method of treating an individual with Parkinson's disease or attention deficit hyperactivity disorder by administering to the individual a therapeutically effective amount of an N,N-dialkyl 3-phenyl-1-indanamine or a mixture of N,N-dialkyl 3-phenyl-1-indanamines.

REFERENCES:
patent: 5639913 (1997-06-01), Lidor et al.
S. Rosonzweig-Lipson et al., "Stereoselective Behavioral Effects of Lu 19-005 in Monkeys: Relation to Binding at Cocaine Recognition Sites," Psychopharmacology, 107:186-194 (1992).
K. P. Bogeso, et al., 3-Phenyl-1-Indanamines Potential Antidepressant Activity and Potent Inhibition of Dopamine, Norepinephrine and Serotonin Uptake, J. Med. Chem., 28:1817-1828 (1985).
S. Izenwasser, et al., "Differential Relationships Among Dopamine Transporter Affinities and Stimulant Potencies of Various Uptake Inhibitors," European Journal of Pharmacology, 263:277-283 (1994).
N. Tomita, "Structure--Activity Relationships of Dopamine--and Norepinephrine-Uptake Inhibitors," Chem. Pharm. Bull. 38(6):1563-1569 (1990).
M. Froimowitz, et al., "Slow Onset, Long Lasting Dopamine Reuptake Blockers as Potential Medications for the Treatment of Cocaine Abuse," 1996 Annual Meeting, Washington, D.C., Nov. 16-21, 1996, Abstract, Mail Date: Aug. 18, 1996.
M. Froimowitz, et al., "Effects of a Slow-Onset, Long-Acting Dopamine Reuptake Blocker on Cacaine Self-Administration and on Nucleus Accumbens Dopamine," Society for Neuroscience Abstracts, vol. 23, Part. 1, 27.sup.th Annual Meeting, New Orleans, LA, Oct. 25-30, 1997, Mail Date: Aug. 25, 1997.
Eliot L. Gardner, et al., Poster presented at meetings of The College on Problems of Drug Dependence, Nashville, Tennessee, Jun. 1997.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Slow-onset, long-lasting dopamine reuptake blockers does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Slow-onset, long-lasting dopamine reuptake blockers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Slow-onset, long-lasting dopamine reuptake blockers will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1073076

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.