Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1984-10-23
1987-05-26
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530322, A61K 3702, C07K 900
Patent
active
046686614
ABSTRACT:
A compound capable of inducing sleep in mammals comprising a peptidoglycan monomer obtained by lysozyme digestion of linear non-crosslinked peptidoglycan polymer chains present in culture fluids of penicillin-treated Brevibacterium divaricatum mutant NRRL 2311 together with hydrolysis of at least one amide group of said monomer.
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Keglevic et al., Eur. J. Biochem., vol. 42, 389-400 (1974).
Keglevic et al., Biochimica et Biophysica Acta, vol. 585, pp. 273-281 (1979).
Tomasic, Biochimica et Biophysica Acta, vol. 629, pp. 77-82 (1980).
Karnovsky Manfred J.
Krueger James M.
Pappenheimer John R.
Phillips Delbert R.
President & Fellows of Harvard College
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