Skraup reaction process for synthesizing quinolones

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546153, 546159, 546168, 546171, 546178, 546181, 546182, C07D21516, C07D21520, C07D21536, C07D21560

Patent

active

061039047

ABSTRACT:
The present invention relates to an improved Skraup reaction process wherein pressure is applied during the reaction and the number of equivalents of sulfuric acid utilized is reduced.

REFERENCES:
patent: 4157445 (1979-06-01), Fitton
patent: 4617395 (1986-10-01), Dockner
patent: 5382502 (1995-01-01), Lau
CA 98:16557, abstract of Roy, Indian J Technol, 1982, vol. 20(8), pp 330-332.
CA 120:163934, abstract of Song, J Heterocyclic Chem, 1993, vol. 30(1), pp 17-21.

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