Skin whitener

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

Reexamination Certificate

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Details

C560S107000

Reexamination Certificate

active

06838481

ABSTRACT:
The invention relates to 5,15-diacetyl-3-benzoyllathyrol compound and a skin whitening composition containing the same. Since the composition of the invention contains 5,15-diacetyl-3-benzoyllathyrol as a melanine production inhibitor, it is excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles. In addition, since it does not induce a secondary effect, it has excellent stability.

REFERENCES:
patent: 4716179 (1987-12-01), Hecker et al.
patent: 0 013 983 (1980-08-01), None
patent: 08-175954 (1996-07-01), None
“Structure of 7-Hydroxy-Lathyrol a Further Diterpene From Euphorbia Lathyris L.”, Narayanan et al., Tetrahedron Letters No. 18, pp. 1325-1328, 1971.
“Constituents of Copper Spurge Seed (Lathyridis Seed) IV the Structure of Ester L3”, Ishiguro et al., Yakugaku Zasshi, vol. 95, No. 6, pp. 760-763, 1975.
“Acyloin Rearrangement in Alpha, Beta-Unsaturated Alpha-Ketols”, Ishiguro et al., Tetrahedron Lett, vol. 5, pp. 315-318, 1975.
“Lathyrane Diterpenes From Euphorbia Lathyris”, Itokawa et al., Phytochemistry, vol. 29, No. 6, pp. 2025-2026, 1990.
“Lathyrol-Benzoate-Diacetate From North American Euphorbia Esula Seeds (Euphorbiaceae)”, Onwukaeme, et al., Ghana Journal of Chemistry 1(4) pp. 202-211, 1991.
“Jatrophane and Lathyrane Diterpenoid Esters From North American Leafy Spurge Seed”, Onwukaeme et al., Phytochemistry, vol. 31, No. 10, pp. 3479-3482, 1992.
International Search Report in PCT/KR99/00768 dated Mar. 24, 2000.
International Preliminary Examination Report in PCT/KR99/00768 dated Aug. 30, 2000.

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