Surgery – Means for introducing or removing material from body for... – With means for cutting – scarifying – or vibrating tissue
Patent
1996-11-22
1998-11-03
Bockelman, Mark
Surgery
Means for introducing or removing material from body for...
With means for cutting, scarifying, or vibrating tissue
601 17, 604 49, A61B 1720
Patent
active
058301771
ABSTRACT:
The present invention provides a methods and apparatuses for use in providing rapid, selective and effective targeted delivery of beneficial substances into hair follicles. The invention relies on the use of vibrational method of delivery of substances of different size from small molecules up to particles compatible with the diameter of hair strand into the hair bulb. The skin is subjected to the vibration of about 1 Hz to about 100 Hz frequency and 0.1 mm to about 10 mm amplitude, an amount which is sufficient to cause mechanical shifts in different directions of skin structure without damage. This results in follicle effective uptake of the tested substances such as carbon particles of different size as well as melanin. The methods and apparatuses of the present invention are particularly useful in conjunction with photosensitive agents and electromagnetic irradiation. Such a combination is used to target the delivery of the agent to within hair follicles and then subsequently activate the agent.
REFERENCES:
patent: 3727607 (1973-04-01), Dill
patent: 4186733 (1980-02-01), Mogaki
patent: 5076305 (1991-12-01), Williams
patent: 5165131 (1992-11-01), Staar
patent: 5311632 (1994-05-01), Center
patent: 5400466 (1995-03-01), Alderman et al.
patent: 5421726 (1995-06-01), Okada
patent: 5538503 (1996-07-01), Henley
Mann et al., Cell, 73:249-261 (1993).
Baranov Eugene
Li Lingna
Anticancer Inc.
Bockelman Mark
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