Skin treatment composition and method of use

Details Skin treatment composition and method of use Skin treatment composition and method of use

1992-05-22

1994-01-25

Rosenbaum, C. Fred

Surgery

Means for introducing or removing material from body for...

Infrared, visible light, ultraviolet, x-ray or electrical...

604 49, 128898, A61N 130

Patent

active

052811964

ABSTRACT:
A composition and method of applying a composition of (a) between about 10 and 15 percent vitamin C, plus or minus 10 percent, by weight to volume, (b) a viscosity agent, and (c) water as the remainder of the composition to healthy surface tissue overlying unhealthy tissue to be treated by radiation therapy for thereby abating dermatitis, mucositis, and esophagitis normally attendant with radiation therapy, the method comprising the steps of identifying the healthy surface tissue in the path of a radiation beam proposed to treat the unhealthy tissue, the identified healthy tissue being pretreated with vitamin C to increase the concentration of ascorbic acid in the identified healthy tissue; applying the composition to the identified healthy tissue; waiting a period of time of about at least one hour prior to radiation therapy so as to allow the vitamin C of the composition to increase the concentration of ascorbic acid in the healthy tissue whereby free radicals from ensuing radiation therapy are scavenged by the increased concentration of ascorbic acid in the healthy tissue; applying therapeutic radiation to the pretreated healthy tissue and the unhealthy tissue in a predetermined target dosage so that unhealthy tissue will be destroyed but so that the increased concentration of ascorbic acid in the healthy tissue will scavenge free radicals from the applied radiation; and scavenging free radicals from the applied radiation by the increased concentration of ascorbic acid in the healthy tissue so that dermatitis, mucositis, and esophagitis normally resulting from radiation therapy are abated.

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patent: 4686235 (1987-08-01), Chang et al.
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patent: 4861783 (1989-08-01), Ackerman et al.
patent: 4975272 (1990-12-01), Voyt
patent: 5078129 (1992-01-01), Kleinberg et al.

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