Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1984-01-23
1987-10-13
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514738, A61K 3120
Patent
active
046999248
ABSTRACT:
A cosmetically acceptable product for topical application to human skin comprises a selected amphiphilic compound having a log partition coefficient in octanol/water of from 0.5 to 3.5; emulsifier which is normally solid at 20.degree. C., which has an average HLB value of from 5 to 11, and which is capable with water of forming a gel phase having an X-ray reflection of from 0.37 to 0.44 nm and which permits substantially no co-crystallisation therewith of the amphiphilic compound; an activity enhancer which is capable, at a concentration of 5% by weight of increasing the cloud point temperature of a 0.025M aqueous solution of polyoxyethylene (8) nonylphenyl ether by at least 10.degree. C.; and water, the product having an aqueous phase and a gel phase.
Optionally the product can also comprise an "oil" having a dielectric constant not greater than 3.0, in which case the product will also comprise an oily phase.
REFERENCES:
patent: 3988470 (1976-10-01), Van Scott et al.
patent: 4105782 (1978-08-01), Yu et al.
patent: 4197316 (1980-04-01), Yu et al.
patent: 4424234 (1984-01-01), Alderson et al.
patent: 4507319 (1985-03-01), Barratt et al.
"A Formulary of Cosmetic Preparations", M. & E. Ash (1977) pp. 259, 291 and 308.
Durrant James A.
Lowry Michael R.
Farrell James J.
Honig Milton L.
Lever Brothers Company
Schenkman Leonard
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