Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1986-07-01
1987-10-27
Brown, J. R.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
514844, A61K 3578
Patent
active
047029153
DESCRIPTION:
BRIEF SUMMARY
The invention relates to a skin regenerating cosmetic composition.
BACKGROUND OF THE INVENTION
There are many excellent compositions on the cosmetic market, the great part of which is based on synthetic elements. The skin regenerating compositions mainly due to their fat and water content improve the condition of the skin. Recently also the use of active ingredients of plant origin is discussed. Because of the great variety of the active ingredients of plant origin only the following are mentioned as examples: grape, palm, fruit of the cocoa tree, gingko leaf (German Patent specifications Nos. 1,492,023, 1,492,118, 1,492,148, 1,617,365, 1,767,098 and 2,232,733). But the plant residues obtained during the processing of agricultural cultivated plants and mainly waste in the preserves industry have not been examined in view of their applicability in the cosmetic industry.
The aim of the present invention was to find new active ingredients of plant origin for use in the cosmetic industry.
Another aim of the present invention was to find plant parts obtained as waste during the processing of agricultural cultivated plants which can be used as active ingredients in cosmetic compositions.
BRIEF DESCRIPTION OF THE INVENTION
During our experiments it has been surprisingly found that by the extraction of the pod and/or grain of green peas an active ingredient, a solution was obtained which was excellently suitable for calming the inflamed skin, improving the scarfskin formation of wounded skin, for light protection, for treating pustules or other inflamatory formations when admixed in a suitable ratio with diluents and/or vehicles and optionally other known substances used in the cosmetic industry, e.g. propolis.
DETAILED DESCRIPTION OF THE INVENTION
The present invention relates to skin regenerating cosmetic compositions comprising the extract of the pod and/or grain of green peas as active ingredient together with the usual vehicles and/or diluents.
The extract is prepared from the pod and/or grain of green peas with water or with a mixture of water and a water miscible organic solvent, preferably with the mixture of ethanol and water by steeping or boiling. After filtering the extract the solution of the active ingredient is formulated directly or after lyophilization with the usual cosmetic vehicles and/or diluents.
The composition of the invention shows a very favorable effect.
The face lotion (Example 7) was examined on 45 women aged from 20 to 65 years. The cream was applied after thorough cleaning twice a day, in the morning and evening. The treatment was continued for two weeks. The following types of face skin were examined: 35 slightly dry, 9 sensitive, dry, 1 very dry skin. The cream has been absorbed well during the treatment, the skin became smooth, velvety. During the treatment no allergic reaction, irritative dermatitis or hypersensitivity were observed.
The body lotion (Example 9) was tested on 32 women aged from 17 to 68 years. The composition was applied after thorough washing twice daily, in the morning and evening. The treatment was continued for two weeks. The following types of skin were examined: 2 normal sensitive, 4 dry sensitive, 18 dry and 8 normal skins. The composition has been absorbed well during each treatment, the skin became velvety, smooth, the skin tightening and dryness which occurred after washing (having a bath or shower) stopped and the skin was calmed and refreshed. No allergic reaction, irritative dermatitis or hypersensitivity was observed.
The following non-limiting Examples show the compositions of the invention and the preparation of the active ingredient.
EXAMPLE 1
Pods of green peas deprived of their grains were dried at room temperature in a manner usual for herbs, then crushed. 1 kg of the crushed substance was suspended in 4.00 liters of water and steeped in a dry, cool place for 24 hours. After filtration the solution was boiled, then a 20% by vol. solution was prepared with cosmetic vaseline oil. The solution was stored in a dry, cool, dark place unti
REFERENCES:
Remington, Practice of Pharmacy, 795-797, 1985.
Hagers Handbuch der Pharmazeutischen Praxis, List, P. H. et al., p. 559, (Springer-Verlag 1977).
Lexikon der Kosmetischen Praxis, Volk, R. et al., pp. 560-563 and 78-79 (1936).
Keri Tibor
Kristof Janosne
Brown J. R.
Dubno Herbert
INNOFINANCE Altalanos Innovacios Penzintezet
Rollins Jr. John W.
Ross Karl F.
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