Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1986-05-07
1990-08-21
Rollins, John W.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
A61K 3578
Patent
active
049504819
DESCRIPTION:
BRIEF SUMMARY
The invention relates to skin regenerating and hydrating cosmetic compositions and to a process for the preparation of the active ingredient.
BACKGROUND OF THE INVENTION
There are many excellent compositions on the cosmetic market, the greater part of which are based on synthetic elements. The skin regenerating compositions produced by the cosmetic factories improve the condition of the skin surface due to their fat and water content. Recently also the use of active ingredients of plant origin is discussed and cosmetic compositions containing herb extracts are on the market as well. The plant residues, which are obtained during the processing of agricultural cultivated plants and mainly as waste in the preserves industry, were not examined in view of the applicability in the cosmetic industry.
The object of the present invention was to obtain plant pieces possibly obtained as waste during the processing of agricultural cultivated plants, the extraction of which results in skin regenerating and hydrating active ingredient solutions.
The maize plant (Zea mays) was chosen for this aim. Maize is an industrial plant which came in Europe from America in 1493 and is known in Europe and now also in America mainly as a cultivated plant. It is cultivated to obtain grains, whereas the hypsophyll consisting of hard fibers, the corn-cob, corn-stalk and corn-silk (corn-beard) are discarded as usual waste.
Due to its mechanical effect the flour obtained from corn-cob has already been used in tooth pastes (HU-PS 118,580), for preparing small sticks for tooth polishing (DE-PS 656,808) and as adsorptive powders for drying exudates in the case of skin diseases caused by exudative dermatitis (U.S. Pat. Nos. 2,890,151 and 3,278,383). Corn-cob flour is also used for treating skin diseases of acne origin (U.S. Pat. No. 3,530,217). No data are, however, described in these patent specifications relating to skin regenerating or hydrating effect of aqueous or alcoholic solutions prepared from corn-cob, corn-cob flour is not used for this purpose. Hair lotion is prepared from the filament of the maize plant according to U.K. Patent No. 856,914; a composition against loss of hair may be prepared from the extract of Artemisia to which optionally also maize beard deception is added (U.K. Patent No. 2,060,378). The skin regenerating and hydrating effects of the maize beard were not, however, examined, and so a composition for this purpose was not produced.
BRIEF DESCRIPTION OF THE INVENTION
From our experiments it has been surprisingly found that by the extraction of the above mentioned pieces of the maize plant an active ingredient solution was obtained which was excellently suitable for calming inflamed skin, improving the scarfskin formation of wounded skin for light protecting, for treating pustules of other inflammatory formations when admixed in a suitable ratio with diluents and/or vehicles and optionally other known substances used in the cosmetic industry, e.g. propolis as disinfectant.
DETAILED DESCRIPTION OF THE INVENTION
The present invention relates to skin regenerating and hydrating cosmetic compositions comprising the extract of nodulous corn-stalk and/or corn hypsophyll and/or corn-cob and/or corn-silk (Zea mays) as active ingredient together with the usual vehicles and/or diluents.
The extract is prepared from the plant pieces with water or with a mixture of water and a water miscible organic solvent, preferably with the mixture of ethanol and water by steeping or boiling.
After filtering the extract the solution of the active ingredient is formulated directly or after lyophilization with the usual cosmetic vehicles and/or diluents.
The compositions of the invention show the expected favorable effect.
The face lotion (Example 9) was examined on 50 women aged from 20 to 63 years. The cream was applied after thorough cleaning twice a day, in the morning and the evening. The treatment was continued for two weeks. The following types of the face skin were examined: 40 slightly dry, 10 sensitive, dry skins. The cream
REFERENCES:
patent: 3530217 (1970-09-01), White et al.
Chem Abstracts 97:124,306b.
Chem. Abstracts 77:132,988p.
Chem. Abstracts 99:209,799f.
Chem. Abstracts 102:23,153r.
Chem. Abstracts 99:138,379f.
Chem. Abstracts 93:148,406c.
Chem. Abstracts 100:48,568b.
Chem. Abstracts 94:28,794p.
Chem. Abstracts 88:92,378k.
Chem. Abstracts 97:195,816d.
Keri Tibor
Kristof Janosne
Dubno Herbert
INNOFINANCE Altalanos Innovacios Penzintezet
Myers Jonathan
Rollins John W.
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