Skin preparations for external use

Details Skin preparations for external use Skin preparations for external use

2001-04-03

2002-10-08

Hartley, Michael G. (Department: 1617)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

C424S093450, C424S114000, C424S758000

Reexamination Certificate

active

06461627

ABSTRACT:

This is a 371 of PCT/JP99/05474, submitted Oct. 5, 1999.
1. Technical Field
The present invention relates to a skin preparation for external use and cosmetics which exhibit excellent effects of ameliorating roughening of the skin and retarding aging of the skin.
2. Background Art
Hitherto, application of soybean extract or soymilk—which is a specific type of soybean extract—to cosmetics has been known, and a number of reports have confirmed its whitening effect. Of such applications, example applications of a fermentation product of soymilk (hereinafter referred to as fermented soymilk) in the field of cosmetics include cosmetics making use of the action of a microorganism belonging to genus Rhizopus (Japanese Patent Application No. 1-102011) and those making use of the action of lactic acid bacteria (Japanese Patent Application No. 3-127713).
However, no published report has mentioned that fermented soymilk is effective in retarding wrinkle formation caused by aging or UV rays, or in ameliorating roughening of the skin.
Accordingly, an object of the present invention is to provide a skin preparation for external use which can ameliorate such conditions of roughening of the skin and formation of wrinkles.
Disclosure of the Invention
In view of the foregoing, the present inventors have conducted extensive researches, and quite surprisingly, have found that when a fermentation product obtained by causing a microorganism belonging to genus Bifidobacterium to act on a soybean extract is subjected to extraction with an organic solvent, there can be obtained a fermented soybean extract which can ameliorate such conditions of roughening of the skin and formation of wrinkles, thus leading to completion of the invention.
Accordingly, the present invention provides a skin preparation for external use which contains a fermented soybean extract prepared by extracting with an organic solvent a fermentation product obtained by treating a soybean extract with one or more microorganisms selected from bifidobacteria.


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Kikuchi-Hayakawa et al, “Effects of soya milk and Bifidobacterium-fermented soya milk on plasma and liver lipids, and faecal steroids in hamsters fed on a cholesterol-free or cholesterol-enriched diet” British Journal of Nutrition (1998) 79, 97-105.*
Scalabrini et al, “Characterization of Bifidobacterium strains for use in soymilk fermentation” International Journal of Food Microbiology (1998) 39, 213-219.*
Matsuyama et al, “Fermentation Profiles and Utilization of Sugars of Bifidobacteria in Soymilk,” Journal of the Japanese Societ for Food Science and Technology (1992) 39, 887-893.

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