Skin permeation enhancer compositions using sucrose esters

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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414448, 414447, A61F 1302

Patent

active

049005553

ABSTRACT:
A method for enhancing the transdermal flux of a transdermally deliverable drug through intact skin is described in which the drug is delivered simultaneously with sucrose monolaurate or a mixture of sucrose esters of coconut fatty acids, which is predominatly sucrose monolaurate. Preferred embodiments of therapeutic systems for delivering the drug and the sucrose ester employ a matrix containing drug at a concentration above saturation.

REFERENCES:
patent: 3598122 (1971-08-01), Zaffaroni
patent: 4130643 (1978-10-01), Smith

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