Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Patent
1987-02-26
1989-09-12
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
424448, A61F 1300
Patent
active
048658480
ABSTRACT:
A method for enhancing the transdermal flux of a transdermally deliverable drug through intact skin is described in which the drug is delivered simultaneously with sucrose monolaurate or a mixture of sucrose esters of coconut fatty acids, which is predominantly sucrose monolaurate. Preferred embodiments of therapeutic systems for delivering the drug and the sucrose ester employ a matrix containing drug at a concentration above saturation.
REFERENCES:
patent: 2893990 (1959-07-01), Hass et al.
patent: 3472931 (1969-10-01), Stoughton
patent: 3527864 (1970-09-01), MacMillan et al.
patent: 3598122 (1971-08-01), Zaffaroni
patent: 3598123 (1971-08-01), Zaffaroni
patent: 3882243 (1985-05-01), Maeda et al.
patent: 3896238 (1975-07-01), Smith
patent: 3903256 (1975-09-01), MacMillan et al.
patent: 3952099 (1976-04-01), Smith
patent: 4046886 (1977-09-01), Smith
patent: 4130643 (1978-12-01), Smith
patent: 4130667 (1978-12-01), Smith
patent: 4144317 (1979-03-01), Higuchi et al.
patent: 4286592 (1981-09-01), Chandrasekaran
patent: 4299826 (1981-11-01), Luedders
patent: 4314557 (1982-02-01), Chandrasekaran
patent: 4335115 (1982-06-01), Thompson et al.
patent: 4343798 (1982-08-01), Fawzi
patent: 4379454 (1983-04-01), Campbell et al.
patent: 4405616 (1983-09-01), Rajadhyaksha
patent: 4568343 (1986-02-01), Leeper et al.
Idson, B., "Percutaneous Absorption", Journal of Pharmaceutical Sciences, vol. 64, No. 6 (Jun. 1975), pp. 901-924.
Chem. Abs., vol. 90, No. 2, #90: 12218y "Surfactants in Suspension. II. Model Experiments in Vitro," Duckova et al.
Chem. Abs., vol. 85, No. 24, #85: 182265a "Shampoos," Minagawa.
Cheng Yu-Ling
Gale Robert M.
Sanders Harold F.
Sugihara Edna
ALZA Corporation
Horne Leon R.
Mandell Edward L.
Page Thurman K.
Sabatine Paul L.
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