Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Patent
1996-05-13
1998-12-01
Brouillette, D. Gabrielle
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
424449, A61F 1302
Patent
active
058434682
ABSTRACT:
Compositions, devices, and methods for transdermal administration of an active agent are disclosed using a novel dual permeation enhancer mixture comprising lauryl acetate and a monoglyceride, preferably glycerol monolaurate. The dual permeation enhancer mixture comprising lauryl acetate is a potent permeation enhancer and provides stable systems which are more readily characterized.
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Shah, Hemanshu S., et al., Drug Development and Industrial Pharmacy, vol. 18 (13), pp. 1461-1476 (1992), "Enhancement Of In Vitro Skin Permeation Of Verapamil".
Beste Russell D.
Burkoth Terry L.
Gale Robert M.
Hamlin Richard D.
Lee Eun Soo
ALZA Corporation
Brouillette D. Gabrielle
Rafa Michael J.
Stone Steve F.
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