Skin permeation enhancer composition for use with sex steroids

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424449, 514946, A61F 1302

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active

056933355

ABSTRACT:
A combination permeation enhancer for increasing the permeability of skin to sex steroids such as estrogens and progestogens comprising a polyhydric thioalcohol of 2 to 6 carbon atoms having at least one mercapto group and at least one hydroxy group and an aliphatic carboxylic acid of 8 to 24 carbon atoms or an ester thereof.

REFERENCES:
patent: 4195095 (1980-03-01), Sheffner
patent: 4637930 (1987-01-01), Konno et al.
patent: 4690683 (1987-09-01), Chien
patent: 5053227 (1991-10-01), Chiang et al.
patent: 5252334 (1993-10-01), Chiang et al.
MTM Research Chemicals, Lancaster Catalogue, pp. 836 and 1206, 1991/92.

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