Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-12-21
1989-12-19
Dixon, Jr., William R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514652, 514657, 514 78, 514272, 514289, 514343, 514357, 514617, 514661, A01N 4336
Patent
active
048883549
ABSTRACT:
The invention is directed to compositions for topical application made up of active pharmaceutical permeants capable of existing in both free base and acid addition salt form. The permeants are present as a combination of both free base and acid addition salt forms. These combined forms provide skin penetration rates which are greater than the penetration rate of either the free base or acid addition salt forms utilized separately. The combined free base-acid addition salt permeants are formulated in a carrier vehicle which preferably also possesses skin penetration enhancement activity.
REFERENCES:
patent: 3337628 (1967-08-01), Crowther et al.
patent: 3520919 (1970-07-01), Crowther et al.
patent: 4537776 (1985-08-01), Cooper
patent: 4600708 (1986-07-01), Reuter et al.
patent: 4731384 (1988-03-01), Dell et al.
"The Merck Index," 7740 Propranolol, p. 7743, 10th Ed., Windholz et al., Merck & Co. Inc., N.J., 1983.
Chang Yunik
Patel Dinesh C.
Dixon Jr. William R.
Medley Margaret B.
TheraTech Inc.
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