Skin lightening agents, compositions and methods

Details Skin lightening agents, compositions and methods Skin lightening agents, compositions and methods

2007-09-18

2007-09-18

Dodson, Shelley A. (Department: 1616)

Drug, bio-affecting and body treating compositions

Bleach for live hair or skin

C424S059000, C424S060000, C424S400000, C424S401000, C514S367000

Reexamination Certificate

active

11394012

ABSTRACT:
Cosmetic compositions and methods, particularly for skin lightening, using N-acylbenzothiazolone compound and derivatives of general formula I as skin lightening agents alone or in combination with other skin benefit agents and together with a cosmetic vehicle:Where R represents a hydrogen atom, C1-C4acyl group, or C1-C4alkyl group. Preferably, the compound is 3-propionylbenzothiazol-2-one, i.e. where R in the formula I is C1alkyl group.

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Ucar, et al., Synthesis and Anticonvulsant Activity of 2(3H)-Benzoxazolone and 2(3H)-Benzothiazolone Derivatives,J. Med. Chem.,41:1138-1145 (1998).
Ucar, et al., “Fries Like” Rearrangement: a Novel and Efficient Method for the Synthesis of 6-Acyl-2(3H)-benzoxazolones and 6-Acyl-2(3H)-benzothiazolones,Tetrahedron54: 1763-1772 (1998).

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