Skin lightening agents, compositions and methods

Drug – bio-affecting and body treating compositions – Topical sun or radiation screening – or tanning preparations

Reexamination Certificate

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Details

C424S060000, C424S400000, C424S401000

Reexamination Certificate

active

06852310

ABSTRACT:
Cosmetic methods of skin lightening using coumarin derivatives of formula I as skin lightening agents alone or in combination with other skin benefit agents and together with a cosmetic vehicle:Where each or both R1and/or R2represents hydrogen; linear or branched C1-C18alkyl, alkenyl, cycloalkyl, cycloalkenyl, hydroxyalkyl, hydroxyalkenyl, acyl, cycloacyl, or alkoxy groups;Each or both R3and/or R4, which may be connected by a single or double carbon-carbon bond (shown as a dotted line), represents hydrogen; linear or branched C1-C18alkyl, alkenyl, alkoxy, cycloalkyl, or cycloalkenyl group; andEach or both R5and/or R6represents a hydrogen atom, OH, C1-C4acyl group, C1-C4alkyl group, O—CO—R7, O—COO—R8group, mesyl group or tosyl group, where each or both R7and/or R8represents hydrogen; linear or branched C1-C18alkyl, alkenyl, hydroxyalkyl, hydroxyalkenyl, acyl, cycloacyl, or alkoxy groups.

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Lille, et al., Tr.Nauch-Issled. Inst. slantsev 1969, No. 18, pp. 127-134.
International Search Report No. PCT/EP 03/08845dated Jan. 2, 2004—3 pp.

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