Skin friendly active substance patch for transdermal...

Details Skin friendly active substance patch for transdermal... Skin friendly active substance patch for transdermal...

2006-02-21

2006-02-21

Page, Thurman K (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

C424S486000, C424S484000, C424S488000, C424S489000, C424S449000, C424S443000

Reexamination Certificate

active

07001613

ABSTRACT:
An active substance matrix patch for controlled delivery of at least one hyperemic active substance to the skin, comprising a flexible cover layer and a water insoluble, pressure sensitive adhesive active substance matrix, wherein said adhesive matrix is free from mineral oils and tackifier resins and comprising:a) from 25 to 90% by weight of synthetic framework polymers based on polyisobutylene,b) from 5 to 40% by weight of amorphous poly-α-olefin,c) from 10 to 60% by weight of an insoluble hydrophilic filler having an average particle size of less than 100 μm, andd) from 0.001 to 20% by weight of the hyperemic active substance.

REFERENCES:
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patent: 5695779 (1997-12-01), Mori
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patent: 6488958 (2002-12-01), Himmelsbach et al.
patent: 2002/0037945 (2002-03-01), Nielsen
patent: 2002/0119185 (2002-08-01), Radloff et al.
patent: 1120115 (2002-08-01), None
patent: WO 9854268 (1998-12-01), None
patent: WO 0045797 (2000-08-01), None
International Search Report from corresponding International Application No. PCT/EP01/12605 dated Jun. 25, 2002.

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