Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice
Reexamination Certificate
2001-11-08
2003-04-22
Criares, Theodore J. (Department: 1617)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Cosmetic, antiperspirant, dentifrice
C514S277000, C514S937000, C514S938000, C514S947000
Reexamination Certificate
active
06551604
ABSTRACT:
TECHNICAL FIELD
The present invention relates to the field of topical compositions for improving the appearance or other condition of skin. More particularly, the invention relates to topical compositions which provide good coverage of skin imperfections, e.g., pores and uneven skin tone, while retaining a natural skin appearance. The compositions of the invention are especially useful for the treatment of hands and other non-facial parts of the body.
BACKGROUND
A variety of compounds have been described in the art as being useful for regulating fine lines, wrinkles and other forms of undesirable skin surface texture. In addition, Vitamin B
3
compounds, particularly niacinamide, have recently been found to provide measurable benefits in regulating skin condition, including regulating fine lines, wrinkles and other forms of uneven or rough surface texture associated with aged or photodamaged skin. However, many materials require multiple applications over an extended period to provide such appearance benefits. It would be additionally advantageous to provide a topical composition which provides a more immediate improvement in the appearance of fine lines, wrinkles, pores and other forms of undesirable skin surface texture, and also to effect an immediate improvement in the feel of the skin.
Particulate materials, including both organic and inorganic particles, have been included in skin care compositions. See, for example, ‘Quantification of the Soft-Focus Effect’, Cosmetics & Toiletries, Vol. 111, July 1996, pp. 57-61, which discloses that one can physically fill in skin lines with a reflective substance such as TiO
2
. U.S. Pat. No. 4,892,726, issued to Toshiba Silicone Co. Ltd. describes the use of polymethylsilsesquioxane powders in makeup and cosmetic compositions which are smooth upon application and impart natural colour. These particles are now available, in a variety of particle size grades, from Toshiba Silicone Co. Ltd under the name Tospearl®. U.S. Pat. No. 5,223,559 describes the use of a variety of particulate fillers of particle size from 0.5 to 50 &mgr;m, particularly from 1 to 15 &mgr;m, for blurring skin defects. The particles disclosed therein include Tospearl® 3120 which has a particle size of about 12 &mgr;m. Furthermore, EP-A-692,242 disclose the. use of hollow, deformable particles of a size of from 1 to 250 &mgr;m, most preferably 18 &mgr;m for reducing the sticky feel of compositions rich in fatty substances. The compositions of EP-A-692,242 can comprise a wide range of biologically active agents, including retinol and its esters.
Whilst the compositions and disclosures of the prior art provide useful advances in the art of cosmetic skin treatment, they do not adequately teach how to provide both acute and chronic improvements in skin feel and appearance, especially for environmentally stressed areas of the body such as hands.
It has now been found that improvements in both the short and long-term appearance and feel of skin can be enhanced by compositions comprising an active for chronically regulating skin condition, e.g., for regulating fine lines, wrinkles, pores and other forms of undesirable skin surface texture, in addition to one or more particulate actives of defined refractive index and particle size.
It is an object of the present invention to provide topical compositions suitable for imparting an essentially immediate improvement in skin feel and appearance. It is another object of the present invention to provide topical compositions containing a particulate material, e.g. polymethylsilsesquioxane, which provides desirable coverage of skin imperfections such as pores arid uneven skin tone, while maintaining a natural skin appearance (e.g. without unacceptable skin whitening). Another object of the present invention is to provide such topical compositions which are additionally useful for chronically regulating skin appearance and/or condition, especially regulating textural or tonal discontinuities in skin (e.g., pores, fine lines, wrinkles, uneven skin colour). It is a particular object of the invention to provide such compositions wherein the composition contains an active for chronically regulating skin condition, in addition to the particulate material.
The present invention also relates to cosmetic methods of improving skin appearance and/or condition by topical application of the subject compositions.
These and other objects of this invention will become apparent in light of the following disclosure.
SUMMARY OF THE INVENTION
The present invention relates to topical compositions comprising:
a) from about 0.5% to about 25% of a first particulate material having a refractive index of from about 1.3 to about 1.7, the particulate material being dispersed in the composition and having a median particle size of from about 2 to about 30 &mgr;m;
b) a safe and effective amount of an active effective for chronically regulating skin condition selected from the group consisting of Vitamin B3 compounds, retinoids, and mixtures thereof; and
c) a topical carrier.
The compositions are useful for imparting an essentially immediate visual improvement in skin appearance, along with additional visual improvements in skin appearance following multiple topical application of the compositions, while maintaining a natural skin appearance.
The invention further relates to cosmetic methods of improving skin appearance and/or condition by topical application of the subject compositions.
DETAILED DESCRIPTION OF THE INVENTION
All percentages and ratios used herein are by weight of the total composition and all measurements made are at 25° C., unless otherwise designated.
All publications cited herein are hereby incorporated by reference in their entirety.
The term “dermatologically-acceptable,” as used herein, means that the compositions or components thereof so described are suitable for use in contact with human skin without undue toxicity, incompatibility, instability, allergic response, and the like.
The term “safe and effective amount” as used herein means an amount of a compound, component, or composition sufficient to significantly induce a positive benefit, preferably a positive skin appearance or feel benefit, including independently the benefits disclosed herein, but low enough to avoid serious side effects, i.e., to provide a reasonable benefit to risk ratio, within the scope of sound medical judgement.
Active and other ingredients useful herein may be categorised or described herein by their cosmetic and/or therapeutic benefit or their postulated mode of action. However, it is to be understood that the active and other ingredients useful herein can in some instances provide more than one cosmetic and/or therapeutic benefit or operate via more than one mode of action. Therefore, classifications herein are made for the sake of convenience and are not intended to limit an ingredient to the particularly stated application or applications listed.
The compositions of the invention are useful for topical application and for providing an essentially immediate (i.e., acute) improvement in skin feel and appearance following application of the composition to the skin. Without intending to be limited by theory, it is believed that this acute improvement results at least in part from therapeutic coverage or masking of skin imperfections by the particulate material. The compositions of the invention are also useful for providing visual improvements in skin appearance or condition following multiple topical applications of the composition to the skin. The compositions provide the visual benefits without imparting an unacceptable skin appearance such as skin whitening.
More particularly, the compositions of the present invention are useful for regulating skin condition, including regulating visible and/or tactile discontinuities in skin, including but not limited to visible and/or tactile discontinuities in skin texture and/or colour, more especially discontinuities associated with skin ageing. Such discontinuities may be induced or caused by internal and/or externa
Beck Petra Helga
Date Robert Francis
Tremblay Mario Elmen
Criares Theodore J.
Kendall Dara M.
Kim Jennifer
Pierre Kenya T.
Rosnell Tara M.
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