Skin care composition

Details Skin care composition Skin care composition

1999-06-03

2003-02-18

Jones, Dameron L. (Department: 1619)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

C424S400000, C424S059000, C424S060000, C424S450000, C424S489000, C424S047000

Reexamination Certificate

active

06521237

ABSTRACT:

FIELD OF THE INVENTION
This invention relates to skin care compositions which include, in a single formulation, the beneficial ingredients for aging or photodamaged skin, retinol and an acid.
BACKGROUND OF THE INVENTION
Retinol or vitamin A alcohol is useful in the reduction of fine lines, wrinkles, and mottled hyperpigmentation in skin. Hydroxy acids, and particularly alpha-hydroxy acids, are useful in increasing the clarity of the skin surface, increasing cellular turnover, and increasing skin radiance and smoothness. Ascorbic acid has skin permeation and collagen synthesis activity.
However, retinol is physically unstable and rapidly degrades when stored at a pH below about 5. Acids such as hydroxy acids, and particularly alpha-hydroxy acids and ascorbic acid, on the other hand, are not active in increasing skin cell turnover, exfoliation, skin permeation, and/or collagen synthesis at pHs above about 5, however.
Consequently, retinol and hydroxy acids and/or ascorbic acid have generally been packaged separately. Retinol typically is packaged in a vehicle at a pH above about 5, while alpha-hydroxy acids and ascorbic acid are packaged at a pH of about 4 or below. Therefore, one must apply two separate products in order to achieve the benefit of both of these ingredients.
The present inventors have discovered a single composition which include both of these ingredients, in which both of these ingredients are stable, and in which both of these ingredients are active upon application to the skin.


REFERENCES:
patent: 5554647 (1996-09-01), Perricone
patent: 5643586 (1997-07-01), Perricone
patent: 5646186 (1997-07-01), Wang et al.
patent: 5665776 (1997-09-01), Yu et al.
patent: 5679374 (1997-10-01), Fanchon et al.
patent: 5744148 (1998-04-01), Habif et al.
patent: 5879690 (1999-03-01), Perricone
patent: 5889054 (1999-03-01), Yu et al.
patent: 5942250 (1999-08-01), Yu et al.
U.S. patent application Ser. No. 09/565,716, pending.
U.S. patent application Ser. No. 09/436,867, pending.
Neutrogena Pore Refining Cream, 1 oz. size product packaging, launched May 11, 1999.

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