Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or...
Reexamination Certificate
2007-05-15
2010-02-23
Mehta, Ashwin (Department: 1638)
Multicellular living organisms and unmodified parts thereof and
Method of introducing a polynucleotide molecule into or...
C435S468000
Reexamination Certificate
active
07667093
ABSTRACT:
A site specific recombination system and methods of use thereof are disclosed for manipulating the genome of higher plants.
REFERENCES:
patent: 5571694 (1996-11-01), Makoff
patent: 5614395 (1997-03-01), Ryals
patent: 5686079 (1997-11-01), Curtiss, III
patent: 5877402 (1999-03-01), Maliga
patent: 6110736 (2000-08-01), Hodges
patent: 6149919 (2000-11-01), Domenighini
patent: 6297054 (2001-10-01), Maliga
patent: 6376744 (2002-04-01), Maliga
patent: 6388168 (2002-05-01), Maliga
patent: 6472586 (2002-10-01), Maliga
patent: 0430645 (1991-06-01), None
patent: 01/77353 (2001-10-01), None
Corneille et al., Plant J., 2001, vol. 27, pp. 171-178.
Kilby et al., Trends in Gen., 1993, vol. 9, pp. 413-421.
Khan, M.S. “Fluorescent antibiotic resistance marker for tracking plastid transformation in higher plants”; Nature Biotechnology, 17: 910-915 (1999).
Dale, E.C. “Gene transfer with subsequent removal of the selection gene from the host genome”, Proc. Natl. Acad. Sci. USA, 88: 10558-10562 (1991).
Srivastava, V. “Single-copy transgenic wheat generated through the resolution of complex integration patterns”; Proc. Natl. Acad. Sci. USA, 96: 11117-11121 (1999).
Le, Y. “Nuclear targeting determinants of the phage P1 Cre DNA recombinase”; Nucleic Acids Research, 27(24): 4703-4709 (1999).
Lyznik, L.A. “Activity of yeast FLP recombinase in maize and rice protoplasts”; Nucleic Acids Research, 21(4): 969-975 (1993).
Lyznik, L.A. “FLP-mediated recombination of FRT sites in the maize genome”; Nucleic Acids Research, 24(19): 3784-3789 (1996).
Zoubenko, O.V. “Efficient targeting of foreign genes into the tobacco plastid genome”; Nucleic Acids Research, 22(19): 3819-3824 (1994).
Love, J. “Stringent control of transgene expression inArabidopsis thalianausing the Top10 promoter system”; The Plant Journal, 21(6): 579-588 (2000).
Serino, G. “A negative selection scheme based on the expression of cytosine deaminase in plastids”; The Plant Journal, 12(3): 697-701 (1997).
Lyznik, L.A. “Heat-inducible expression of FLP gene in maize cells”; The Plant Journal, 8(2): 177-186 (1995).
Soll, J. “Protein translocation into and across the chloroplastic envelope membranes”; Plant Molecular Biology, 38: 191-207 (1998).
Adams, D. “Cre-iox Recombination inEscherichia coliCells Mechanistic Differences from the in Vitro Reaction”; J. Mol Biol., 226: 661-673 (1992).
Craig, N.L. “The Mechanism of Conservation Site-Specific Recombination”: Annu. Rev. Genet. 22: 77-105 (1988).
Lichtenstein, C. “Prospects for reverse genetics in plants using recombination”; Plant Molecular Biology, 21: v-xii (1993).
Lubben, T.H. “Chloroplast import characteristics of chimeric proteins”; Plant Molecular Biology: 12: 13-18 (1989).
Russell, S.H. “Directed excision of a transgene from the plant genome”; Mol Gen Genet, 234: 45-59 (1992).
Timko, M.P. “Structure and Expression of Nuclear Genes Encoding Polypeptides of the Photosynthetic Apparatus”; Mol Biol of the Photosynthetic Apparatus, 381-396 (1985).
Timmermans, M.C.P. “The pFF plasmids: cassettes utilising CaMV sequences for expression of foreign genes in plants”; Journal of Biotechnology, 14: 333-344 (1990).
Wasmann, C.C. “The Importance of the transit peptide and the transported protein for protein import into chloroplasts”; Mol Gen Genet, 205: 446-453 (1986).
Gianelli et al., Infect. Immun., 1997, vol. 65, pp. 331-334.
Pizza, M. “A Genetically Detoxified Derivative of Heat-labileEscherichia coliEnterotoxin Induces Neutralizing . . . ”; J. Exp. Med., 180: 2147-2153 (1994).
Ma, S.W. “Transgenic plants expressing autoantigens fed to mice to induce oral immune tolerance”; Nature Medicine; 3(7): 793-796 (1997).
Kuroda, H. “Complementarity of the 16S rRNA penultimate stem with sequences downstream of the AUG destabilized the plastid mRNAs”; Nucleic Acids Research, 29-4: 970-975 (2001).
Kuroda, H. “Sequences Downstream of the Translation Initiation Codon Are Important Determinants of Translation Efficiency in Chloroplasts”; Plant Phys, 125: 430-436 (2001).
Ye, G. “Plastid-expressed 5-enolpyruvylshikimate-3-phosphate synthase genes provide high level glyphosate tolerance in tobacco”; The Plant Journal, 25(3): 261-270 (2001).
Staub, J.M. “High-yield production of human therapeutic protein in tobacco chloroplasts”; Nature Biotechnology, 18: 333-338 (2000).
Heifetz, P.B. “Genetic engineering of the chloroplast”; Biochimie, 82: 655-666 (2000).
Giddings, G. “Transgenic plants as factories for biopharmaceuticals”; Nature Biotechnology, 18: 1151-1155 (2000).
Douce, G. “Genetically Detoxified Mutants of Heat-Labile Toxin fromEscherichia coliAre Able To Act as Oral Adjuvants”; Infection and Immunity, 67(9): 4400-4406 (1999).
Douce, G. “Mucosal immunogenicity of genetically detoxified derivatives of heat labile toxin fromEscherichia coli”; Vaccine, 16(11/12): 1065-1073 (1998).
Barchfeld, G.L. “The adjuvants MF59 and LT-K63 enhance the mucosal and systemic immunogenicity of subunit influenza vaccine administered in mice”; Vaccine, 17: 695-704 (1999).
Carrier, H. “Kanamycin resistance as a selectable marker for plastid transformation in tobacco”; Mol Gen Genet, 241: 49-56 (1993).
Hajdukiewicz, P. “Multiple pathways for Cre/lox-mediated recombination in plastids” The Plant Journal, 27(2): 161-170 (2001).
Daniell, H. “Marker free transgenic plants: engineering the chloroplast gene without the use of antibiotic selection” Curr. Genet., 39: 109-116 (2001).
Tacket, C. “Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato” Nature Medicine, 4(5): 607-609 (1998).
Tacket, C. “A review of oral vaccination with transgenic vegetables” Microbes and Infection, 777-783 (1999).
Tregoning, J. “Expression of tetanus toxin Fragment C in tobacco chloroplasts” Nucleic Acids Research, 31(4): 1174-1179 (2003).
Bock, R. “Transgenic Plastids in Basic Research and Plant Biotechnology” J. Mol. Biol., 312: 425-438 (2001).
Magagnoli, C. “Mutations in the A Subunit Affect Yield, Stability, and Protease Sensitivity of Nontoxic Derivates . . . ” Infection and Immunity, 64(12): 5434-5438 (1996).
Corneille Sylvie
Lutz Kerry
Maliga Pal
Dann Dorfman Herrell & Skillman
Mehta Ashwin
Rigaut Kathleen D.
Rutgers The State University of New Jersey
LandOfFree
Site-specific recombination system to manipulate the plastid... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Site-specific recombination system to manipulate the plastid..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Site-specific recombination system to manipulate the plastid... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4167376