Site specific mutagenesis in alpha-1-antitrypsin

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435 70, 4351723, 4353171, 935 10, 935 8, C12P 1934, C12P 2102, C12N 1500, C12N 100

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active

047118482

ABSTRACT:
Methods are provided for producing sites specific mutagenized alpha-1-antitrypsin. Particular mutants are formed having a mutation in the active site of alpha-1-antitrypsin at amino acid position 358 and at amino acid position 342.

REFERENCES:
patent: 4351901 (1982-09-01), Bahl
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