Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2002-04-30
2008-09-16
Duffy, Patricia A (Department: 1645)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S252300, C435S320100
Reexamination Certificate
active
07425449
ABSTRACT:
Site-specificListeriaintegration vectors and methods for their use are provided. The subject vectors include a bacteriophage integrase gene and a bacteriophage attachment site, where in many embodiments the bacteriophage that is the source of these elements is a listeriophage. In certain embodiments, the subject vectors further include a multiple cloning site, where the multiple cloning site may further include a polypeptide coding sequence, e.g., for a heterologous antigen. The subject vectors and methods find use in a variety of different applications, including the study ofListeriaspecies and the preparation ofListeriavaccines.
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Calendar Richard
Lauer Peter M.
Portnoy Daniel A.
Bozicevic Field & Francis LLP.
Duffy Patricia A
Field Bret E.
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