Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1990-03-08
1994-06-14
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 231, 536 2532, 536 2533, 435 6, C07H 2100
Patent
active
053211316
ABSTRACT:
Disclosed are compounds consisting of a plurality of nucleosides which are covalently linked by at least one aminoalkylphosphoramidate linkage of the formula ##STR1## wherein n=2 to 6 and Nu.sub.1 and Nu.sub.2 represent nucleoside phosphates.
REFERENCES:
patent: 4547569 (1985-10-01), Letsinger et al.
patent: 4762779 (1988-08-01), Snitman
patent: 4837312 (1989-06-01), Dervan et al.
patent: 4958013 (1990-09-01), Letsinger
patent: 4959463 (1990-09-01), Froehler et al.
patent: 4965349 (1990-10-01), Woo et al.
Nevinskii et al., Chemical Abstracts: vol. 99, No. 5, 35050n, Aug. 1, 1983.
Dobronravova et al., Chemical Abstracts: vol. 98, No. 7, 54383u, Feb. 14, 1983.
Cardullo et al., Proc. Natl. Acad. Sci. USA 85:8790-8794 (1988).
Haralambidis et al., Nucleic Acids Res. 18:501-505 (1990).
Helene & Toulme, Oligonucleotides. Ed. Cohen, MacMillan Press, pp. 137-167 (1989).
Matthews & Kricka, Analytical Biochem. 169:1-25 (1988).
Nelson et al., Nucleic Acids Res. 17:7187-7194 (1989).
Zwierzak, A., Communications. 507-509 (1975).
Froehler & Matteucci, Nucleic Acids Res. 16:4831-4839 (1988).
Letsinger et al., J. Am Chem. Soc. 110:4470-4471 (1988).
Jager et al., Biochemistry. 27:7237-7246 (1988).
Caruthers et al., Methods in Enzymology. 154:287-313 (1987).
Agrawal et al., Nucleic Acids Res. 14:6227-6245 (1986).
Le Doan et al., Nucleic Acids Res. 15:8643-8659 (1987).
Agrawal & Goodchild, Tetrahedron Lett. 28:3539-3542 (1987).
Agrawal et al., Proc. Natl. Acad. Sci. USA, 85:7079-7083 (1988).
Agrawal, S., Tetrahedron Lett. 30:7025-7028 (1989).
Fidanza & McLaughlin, J. Am. Chem. Soc. 111:9117-9119 (1989).
Haralambidis et al., Nucleic Acids Res. 18:493-499 (1990).
Agrawal et al. J. Cell Biology 107:468-483 (1988).
Agrawal Sudhir
Tang Jinyan
Brown Johnnie R.
Hybridon, Inc.
Wilson J. Oliver
LandOfFree
Site-specific functionalization of oligodeoxynucleotides for non does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Site-specific functionalization of oligodeoxynucleotides for non, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Site-specific functionalization of oligodeoxynucleotides for non will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1250232