Site-specific drug delivery

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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Details

C436S501000, C514S707000, C530S350000, C536S115000, C536S054000, C536S053000, C536S018700

Reexamination Certificate

active

07033765

ABSTRACT:
Compounds and methods which are useful for the site-specific delivery and localization of drugs are provided. The compounds can be represented by the formula: A-L-D wherein A is an anchoring moiety; L is a linking group; and D is a drug.

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L.D. Small, “Synthesis and Preliminary Antimicrobial Screening of Two Thiosulfonates,”Journal of Pharmaceutical Sciences, 65 (No. 11): 1692-1694 (1976).
Foong et al., “Development of a Novel Thiol Reagent for Probing Ion Channel Structure: Studies in a Model System,”Biochemistry, 36:1343-1348 (1997).

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