Site-specific adhesion within the GI tract using nanoparticles s

Details Site-specific adhesion within the GI tract using nanoparticles s Site-specific adhesion within the GI tract using nanoparticles s

1995-02-15

1996-12-03

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424498, 514937, 514938, 514939, 514943, A61K 9107, A61K12300

Patent

active

055805795

ABSTRACT:
Nanoparticulate crystalline therapeutic or diagnostic substances formulated with stabilizers and high molecular weight, linear poly(ethylene oxide) polymers, enhance contact between the crystalline therapeutic or diagnostic substances and the gastrointestinal tract providing site-specific and extended therapeutic or diagnostic effect.

REFERENCES:
patent: 5145684 (1992-09-01), Liversidge et al.
Kinam Park and Joseph R. Robinson, "Bioadhesive polymers as platforms for oral-controlled drug delivery: method to study bioadhesion", 1984, pp. 107-127.

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