SISP-1, a novel p53 target gene and use thereof

Details SISP-1, a novel p53 target gene and use thereof SISP-1, a novel p53 target gene and use thereof

2007-02-27

2010-02-02

Leavitt, Maria (Department: 1633)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S320100, C435S325000

Reexamination Certificate

active

07655778

ABSTRACT:
The present invention relates to a novel p53 target gene SISP-1 (Stress induced Secreted Protein 1) and a SISP-1 protein encoded by the gene. The SISP-1 protein of the present invention induces apoptosis by interaction with p53. The present invention provides the use of the gene/protein associated with treating abnormal apoptosis such as tumor.

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NCBI GenBank AY265805.1.

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