Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2011-05-17
2011-05-17
McGarry, Sean R (Department: 1635)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C536S023100, C536S024100, C536S024500, C435S006120, C435S375000
Reexamination Certificate
active
07943589
ABSTRACT:
The invention provides a microbicidal composition comprising at least one siRNA. The siRNA is an RNA duplex made of one or two molecules. A portion of the siRNA is identical to a target sequence in an essential gene of a virus. The virus may be a herpesvirus, for example, HSV-1 or HSV-2. Preferably, the herpesvirus is HSV-2. The microbicidal composition further comprises a pharmaceutically acceptable carrier. Also included in the invention are methods to prevent and treat viral infections by administration of the microbicidal composition. Preferably, the microbicidal composition is administered transmucosally.
REFERENCES:
patent: 5248670 (1993-09-01), Draper et al.
patent: 5514577 (1996-05-01), Draper et al.
patent: 5658891 (1997-08-01), Draper et al.
patent: 6310044 (2001-10-01), Draper et al.
patent: 6821519 (2004-11-01), Day et al.
patent: 7358068 (2008-04-01), Vaillant et al.
patent: 7696179 (2010-04-01), Lieberman et al.
patent: 2003/0165476 (2003-09-01), Orson et al.
patent: 2003/0165820 (2003-09-01), Day et al.
patent: 2006/0293271 (2006-12-01), McSwiggen et al.
patent: 2153686 (1985-08-01), None
patent: 99/49067 (1999-09-01), None
patent: 0176624 (2001-10-01), None
patent: 02094185 (2002-11-01), None
patent: 2004062591 (2004-07-01), None
patent: 2005042705 (2005-05-01), None
patent: 2005042716 (2005-05-01), None
Schultz et al., Investigative Opthalmology & Visual Science vol. 45. suppl.[1], p. U596, 2004, E absract 1651(2 pages).
Knipe David
Lieberman Judy
Palliser Deborah
Immune Disease Institute, Inc.
McGarry Sean R
Nixon & Peabody LLP
President and Fellows of Harvard College
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