Sinus delivery of sustained release therapeutics

Details Sinus delivery of sustained release therapeutics Sinus delivery of sustained release therapeutics

2004-03-12

2009-06-09

Sirmons, Kevin C (Department: 3767)

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

C604S510000, C604S514000

Reexamination Certificate

active

07544192

ABSTRACT:
The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.

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