Single-stranded labelled oligonucleotides of preselected sequenc

Details Single-stranded labelled oligonucleotides of preselected sequenc Single-stranded labelled oligonucleotides of preselected sequenc

1994-11-09

1996-07-30

Robinson, Douglas W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2431, 536 2432, 435 6, C07H 2100

Patent

active

055413137

ABSTRACT:
Substantially pure single-stranded oligonucleotides having a preselected sequence of not more than about 200 nucleotides, at least one of which is at a preselected position in the sequence and includes a base with a covalently attached linker arm containing or capable of binding at least one reporter group or solid support. A process for the chemical synthesis of the substantially pure single-stranded oligonucleotide and modified nucleosides useful in such synthesis are provided.

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