Single stranded DNA binding proteins from Archaea and uses...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S091200, C530S350000, C530S358000, C536S023700

Reexamination Certificate

active

07666591

ABSTRACT:
The invention provides ssDNA-binding proteins from three species of archaeons,Methanococcus jannaschii, Methanobacter theromoautotrophicum, andArchaeoglobus fulgidus, as well as the ability to identify ssDNA-binding proteins from other archaeons. The proteins help render DNA more accessible to DNA polymerase and are robust reagents for a variety of biotechnical processes, including PCR. The invention further provides nucleic acids encoding such proteins, vectors for transfecting host cells, host cells comprising the vectors, and methods of using the proteins.

REFERENCES:
patent: 5449603 (1995-09-01), Nielson et al.
patent: 5605824 (1997-02-01), Nielson et al.
patent: 5646019 (1997-07-01), Nielson et al.
patent: 5773257 (1998-06-01), Nielson et al.
patent: 6503729 (2003-01-01), Bult et al.
patent: 6852832 (2005-02-01), Kowalczykowski et al.
patent: 2004/0180342 (2004-09-01), Haseltine et al.
Cubeddu, L., et al., “Structural and functional characterization ofSolfolobus solfactaricusSSB and its interaction with DNA,” FASEB Summer Research, 2002, Poster Abstract, 1 pg.
Cubeddu, L., et al., “Structural and calorimetric studies of an archaeal single-stranded DNA binding protein,” European Conference on Current Trends in Microcalorimetry: Applications of Biocalorimetry (ABC III), Aug. 27-30, 2002, Dublin, Ireland, Abstract, 1 pg.
Haseltine, C., et al., “A distinctive single-stranded DNA binding protein from the ArchaeonSulfolobus solfataricus,” Molecular Microbiology, 2002, vol. 43, No. 6, pp. 1505-1515.
Kerr, I., et al., “Overexpression, purification, crystallization and data collection of a single-stranded DNA-binding protein fromSulfolobus solfataricus,” Acta Cryst., 2001, vol. D57, pp. 1290-1292.
Kerr, I., et al., “Insights into ssDNA Recognition by the OB Fold from a Structural and Thermodynamic Study of Sulfolobus SSB Protein;” 2003; The EMBO Journall vol. 22; No. 11; pp. 2561-2570.
She, Q., et al., “The complete genome of the crenarchaeonSulfolobus solfataricusP2,” PNAS, Jul. 3, 2001, vol. 98, No. 14, pp. 7835-7840.
Bochkarev, A.,Nature385, 176-181 (1997).
Bochkareva, E., et al.,J. Biol. Chem. 273, 3932-3947 (1998).
Bult, C. J. et al., Science 273:1058-1073 (1996).
Bult, et al., NCBI, National Library of Medicine, NIH (Bethesda, MD, USA) Accession No. F64444, Sep. 1996.
Chedin et al., TIBS 23:273-277 (1998).
Fairman, M. P. et al.,Embo J. 7, 1211-1218 (1988).
Gomes, X. V.Biochemistry35, 10558-10568 (1996).
Henricksen, L. A.,Nucleic Acids Res. 24, 3107-3112 (1996).
Kelly, et al.,PNAS95(25):14634-9 (1998).
Kim et al., Biochemistry, 33:14197-206 (1994).
Kim et al., Mol. Cell Biol., 12:3050-3059.
Klenk, H. P. et al.,Nature390, 364-370 (1997).
Lin, Y.-L. et al.,J. Biol. Chem. 273, 1453-1461 (1996).
Lohman, T. M. et al.,Annu. Rev. Biochem. 63, 527-570 (1994).
Philipova, D. et al.,Genes Dev. 10, 2222-2233 (1996).
Sancar, A., et al.,Proc. Natl. Acad. Sci. USA78, 4274-4278 (1981).
Sreenivas, Biochemistry and Molecular Biology International (Feb. 1998) 44: 269-282.
Shamoo, Y. et al.,Nature376, 362-366 (1995).
Smith, D. R. et al.J. Bacteriol. 179, 7135-7155 (1996).
Wold, M. S.,Annu. Rev. Biochem. 66, 61-92 (1997).

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