Single stage resolution/racemization of .alpha.-amino-.epsilon.-

Details Single stage resolution/racemization of .alpha.-amino-.epsilon.- Single stage resolution/racemization of .alpha.-amino-.epsilon.-

1975-04-07

1976-10-26

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26029386, 2603265FL, C07D22308

Patent

active

039883205

ABSTRACT:
Resolution of .alpha.-amino-.epsilon.-caprolactam with simultaneous racemization of the undesired D-.alpha.-amino-.epsilon.-caprolactam enantiomer is effected by forming a coordinately saturated .alpha.-amino-.epsilon.-caprolactam complex with NiCl.sub.2, preferably crystallizing the L-.alpha.-amino-.epsilon.-caprolactam complex in the presence of fine seed crystals of L-.alpha.-amino-.epsilon.-caprolactam complex of NiCl.sub.2 and catalytic amounts of a strong base selected from the alkoxides or hydroxides of Ni(II) and recovering L-.alpha.-amino-.epsilon.-caprolactam hydrochloride from the crystalline product.

REFERENCES:
patent: 3024231 (1962-03-01), Scherrer
patent: 3105067 (1963-09-01), Nelemans et al.
patent: 3275619 (1966-09-01), Brenner et al.
patent: 3542766 (1970-11-01), Ohnogi et al.
patent: 3591579 (1971-07-01), Shibahara et al.
patent: 3658811 (1972-04-01), Tanaka et al.
patent: 3692775 (1972-09-01), Kubanek et al.
patent: 3824231 (1974-07-01), Kubanek et al.
patent: 3842073 (1974-10-01), Fuhrmann et al.

Affiliated with

Also associated with

Rating

Single stage resolution/racemization of .alpha.-amino-.epsilon.- does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Single stage resolution/racemization of .alpha.-amino-.epsilon.-, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Single stage resolution/racemization of .alpha.-amino-.epsilon.- will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-184151