Single-stage process for preparing mixed-substituted 1,2-diacyl-

Details Single-stage process for preparing mixed-substituted 1,2-diacyl- Single-stage process for preparing mixed-substituted 1,2-diacyl-

1987-11-10

1989-03-21

Garvin, Patrick P.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260389, 548112, 548113, C07F 910

Patent

active

048141127

ABSTRACT:
Single-stage process for preparing mixed-substituted enantiomerically pure 1,2-diacyl-sn-glycero-3-phosphocholines of general formula I ##STR1## in which R.sub.1 and R.sub.2 are different and independently of each other denote a substituted or unsubstituted C.sub.1 to C.sub.24 -alkyl or C.sub.3 to C.sub.24 -alkenyl radical, by reacting 1-0-triphenylmethyl-2-acyl-sn-glycero-3-phosphocholine of the general formula ##STR2## in which T denotes a substituted or unsubstituted triphenylmethyl group and R.sub.2 is as defined above, with a reactive carboxylic acid derivative of the general formula

REFERENCES:
patent: 3577446 (1971-05-01), Rakhit
patent: 4622180 (1986-11-01), Paltauf et al.
patent: 4710579 (1987-12-01), Nujima et al.
patent: 4717512 (1988-01-01), Paltauf et al.
"The Nomenclature of Lipids", Biochem. J. 171 (1978), pp. 29-35.

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