Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample
Reexamination Certificate
2006-04-04
2006-04-04
Le, Long V. (Department: 1641)
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Means for analyzing liquid or solid sample
C422S068100, C422S050000, C257S236000, C204S290010, C204S290030, C204S290050
Reexamination Certificate
active
07022287
ABSTRACT:
The present invention discloses an electrochemical device for detecting single particles, and methods for using such a device to achieve high sensitivity for detecting particles such as bacteria, viruses, aggregates, immuno-complexes, molecules, or ionic species. The device provides for affinity-based electrochemical detection of particles with single-particle sensitivity. The disclosed device and methods are based on microelectrodes with surface-attached, affinity ligands (e.g., antibodies, combinatorial peptides, glycolipids) that bind selectively to some target particle species. The electrodes electrolyze chemical species present in the particle-containing solution, and particle interaction with a sensor element modulates its electrolytic activity. The devices may be used individually, employed as sensors, used in arrays for a single specific type of particle or for a range of particle types, or configured into arrays of sensors having both these attributes.
REFERENCES:
patent: 5181526 (1993-01-01), Yamasaki
patent: 5393401 (1995-02-01), Knoll
patent: 5891630 (1999-04-01), Eggers et al.
patent: 6258652 (2001-07-01), Stacey
patent: 6358819 (2002-03-01), Shelton et al.
patent: 6566276 (2003-05-01), Maloney et al.
patent: 6653653 (2003-11-01), Brousseau, III
patent: 6673717 (2004-01-01), Brousseau, III
patent: 2004/0005243 (2004-01-01), Mulhern et al.
Flounders Albert W.
Hughes Robert C.
Janek Richard P.
Kravitz Stanley H.
Ricco Antonio J.
Evans Timothy P.
Le Long V.
Sandia National Laboratories
Yu Melanie
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