Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...
Patent
1983-05-26
1986-08-12
Spear, Frank
Liquid purification or separation
Processes
Liquid/liquid solvent or colloidal extraction or diffusing...
2104332, 604 6, B01D 1300
Patent
active
046055037
ABSTRACT:
A single needle batch-type blood fractionation system for separating plasma from whole blood includes a disposable flow system having a single-lumen phlebotomy needle and associated donor conduit, a flow-through plasma separation filter, and an in-process fluid reservoir. During an initial draw cycle whole blood is pumped through the filter to the in-process reservoir by a peristaltic-type inlet pump operating at a predetermined draw rate. When a predetermined volume of filtered plasma-deficient blood has been collected in the reservoir, as sensed by the weight of the reservoir, the system reverts to a return cycle wherein a portion of the plasma-deficient blood in the reservoir is pumped back to the donor conduit by a peristaltic-type return pump operating at a predetermined return rate higher than the draw rate of the inlet pump. Depending on the relative operating speeds of the inlet and return pumps, an operator-controllable portion of the plasma-deficient blood from the in-process reservoir is returned to the donor through the phlebotomy needle, and the remaining portion is recirculated through the filter. The partial recirculation of plasma-deficient blood through the filter during the return mode reduces the processing time of the system, provides for improved accommodation of whole blood of unusually high or low hematocrit, and enables the use of a smaller and less expensive filter.
REFERENCES:
patent: 3472765 (1969-10-01), Budd et al.
patent: 3567031 (1971-03-01), Loeffler
patent: 3682172 (1972-08-01), Freedman et al.
patent: 3699960 (1972-10-01), Freedman
patent: 3705100 (1972-12-01), Blatt et al.
patent: 3802432 (1974-04-01), Djerassi
patent: 3890969 (1975-06-01), Fischel
patent: 3927980 (1975-12-01), Leonard
patent: 3953329 (1976-04-01), Updike
patent: 3967777 (1976-07-01), Canevari
patent: 4013564 (1977-03-01), Nose
patent: 4026669 (1977-05-01), Leonard et al.
patent: 4191182 (1980-03-01), Popovich et al.
patent: 4209392 (1980-06-01), Wallace
patent: 4343705 (1982-08-01), Legg
patent: 4447191 (1984-05-01), Bilstad et al.
Bilstad et al., "Blood Fractionation Apparatus", International Publication No. WO81/02979, 10-1981.
Bilstad Arnold C.
Brown Richard I.
Kruger Robert J.
Baxter Travenol Laboratories Inc.
Cummings Eugene M.
Price Bradford R. L.
Ryan Daniel D.
Spear Frank
LandOfFree
Single needle blood fractionation system having adjustable recir does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Single needle blood fractionation system having adjustable recir, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Single needle blood fractionation system having adjustable recir will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1934748