Single dosage semi-solid topical pharmaceutical forms for transd

Details Single dosage semi-solid topical pharmaceutical forms for transd Single dosage semi-solid topical pharmaceutical forms for transd

1995-12-20

1997-11-11

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424449, 424444, 424455, 424478, 424490, A61K 914

Patent

active

056861125

ABSTRACT:
To improve the efficacy and tolerability of customary topical applications for transdermal systemically acting pharmaceutical substances, single dosage topical pharmaceutical forms which are therapeutically exactly ready-to-administer are formed from suitable semi-solid pharmaceutical forms. The topical single doses are specified pharmaceutically with respect to their dose, their topical spreading behaviour and their permeation properties. Several of the topically ready-to-administer single doses are in this case accommodated in a common commercial packaging container. Complex treatments can be developed by means of different individual dosages or alternatively active compound combinations. As pharmacological active compounds, steroids, peptides, various analgesics, local anaesthetics and non-steroidal antirheumatics are employed in particular. The single dosage topical pharmaceutical form is a safe, easy to administer and inexpensive application form which makes possible a more exact topical therapy for systemic administrations than could previously be achieved using conventional topical administration forms.

REFERENCES:
patent: 4927687 (1990-05-01), Nuwayser
patent: 5232703 (1993-08-01), Blank
patent: 5234957 (1993-08-01), Mantelle

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