Simultaneous radioassay of folate and vitamin B.sub.12

Details Simultaneous radioassay of folate and vitamin B.sub.12 Simultaneous radioassay of folate and vitamin B.sub.12

1977-07-21

1979-03-27

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 424 12, G01N 3316

Patent

active

041466020

ABSTRACT:
A serum sample is heated at an alkaline pH to release folate and vitamin B.sub.12 from endogenous binders. A simultaneous radioassay for folate and vitamin B.sub.12 is effected by contacting the sample with binder for folate, binder for vitamin B.sub.12, folote labeled with one radioactive isotope and vitamin B.sub.12 labeled with another radioactive isotope, followed by separation of bound and free portions, and determination of the radioactivity of at least one of the portions. The amounts of folate and vitamin B.sub.12 present in the sample may be determined from standard curves.

REFERENCES:
patent: 3937799 (1976-02-01), Lewin et al.
patent: 3952091 (1976-04-01), Grunberg et al.
patent: 3972991 (1976-08-01), Caston et al.
patent: 3981863 (1976-09-01), Niswender et al.
patent: 3988431 (1976-10-01), Givas et al.
Merrett et al, Clinica Chimica Acta, vol. 65, No. 1, Nov. 15, 1975, pp. 131-134.

Affiliated with

Also associated with

Rating

Simultaneous radioassay of folate and vitamin B.sub.12 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Simultaneous radioassay of folate and vitamin B.sub.12, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Simultaneous radioassay of folate and vitamin B.sub.12 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1821806