Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Attached to antibody or antibody fragment or immunoglobulin;...
Patent
1974-10-23
1976-04-20
Wolk, Morris O.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Attached to antibody or antibody fragment or immunoglobulin;...
23230B, 232303, 260112B, 424 12, 252408, G01N 3316
Patent
active
039520919
ABSTRACT:
Compositions useful for conducting a plurality of different radioimmuno-assays simultaneously and methods for preparing same. The compositions radioimmunoassaya a plurality of labeled antigens and their respective antibodies present in selected concentrations so that the response curves observed for each antigen are essentially superimposable on the response curve of all other antigens present in the composition. Particularly preferred compositions include a mixture of radiolabeled morphine, a radiolabeled 5- or 5,5-substituted barbituric acid, i.e., secobarbital and their respective antibodies useful for performing a bivalent radioimmunoassay and a mixture of radiolabeled morphine, radiolabeled amphetamine, a radiolabeled 5- or 5,5-substituted barbituric acid and their respective antibodies useful for performing a trivalent radioimmunoassay.
REFERENCES:
patent: 3704282 (1972-11-01), Spector
patent: 3709868 (1973-01-01), Spector
patent: 3766162 (1973-10-01), Spector
patent: 3775536 (1973-11-01), Spector
patent: 3799741 (1974-03-01), Williams
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patent: 3843696 (1974-10-01), Wagner
patent: 3853987 (1974-12-01), Dreyer
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patent: 3878187 (1975-04-01), Schneider
Gomez Magdalena Usategui
Grunberg Emanuel
Gould George M.
Hoffmann-La Roche Inc.
Marantz Sidney
Welt Samuel L.
Wolk Morris O.
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