Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1977-01-21
1980-06-10
Padgett, Benjamin R.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
23230B, 424 8, 424 12, G01N 3316, A61K 4300
Patent
active
042073073
ABSTRACT:
This invention includes an antigenic conjugate of ecgonine and a carrier which elicits anti-benzoylecgonine (cocaine metabolite) serum useful for the detection of cocaine metabolites in human organs and body fluids by immunoassay. The invention also includes the method of producing the anti-benzoylecgonine serum, the immunoassay method and composition including the anti-benzoylecgonine serum and a labeled benzoylecgonine and a non-labeled benzoylecgonine.
The invention also includes a composition comprising a plurality of antigenic conjugates which elicit a multivalent anti-serum capable of complexing a plurality of antigens in a multiple immunoassay detection method. The invention includes the method of producing the multivalent anti-serum and an immunoassay method employing the multivalent anti-serum. The invention further includes a composition comprising the multivalent anti-serum and a plurality of labeled antigens and non-labeled antigens.
REFERENCES:
patent: 3888866 (1975-06-01), Leute et al.
patent: 3917582 (1975-11-01), Soffer et al.
patent: 3952091 (1976-04-01), Grunberg et al.
patent: 4022878 (1977-05-01), Gross
patent: 4031199 (1977-06-01), Nieschulz et al.
patent: 4045420 (1977-08-01), Soffer et al.
Davidow Bernard
Kaul Balkrishena
Millian Stephen J.
Clarke Dennis P.
Nucker Christine M.
Padgett Benjamin R.
Research Corporation
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