Simultaneous assay for T and B lymphocyte populations and subpop

Chemistry: analytical and immunological testing – Involving iga – igd – ige – or igm

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436519, 436523, 436531, 436533, 436534, 436548, G01N 3354

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active

045116628

ABSTRACT:
An assay for simultaneously determining the ratio of B cells and T cells to the total cell population and subpopulations thereof present in a lymphocyte population utilizes excess amounts of B cell binding protein and T cell binding protein bound to solid phase particles. By exposing the particles to the lymphocyte population, rosettes are formed which may be visually distinguished and counted under a microscope, yielding the proportions of B cells and T cells, including any subpopulations for which a specific label was provided. Macrophages may be identified by their ability to ingest the particles.

REFERENCES:
patent: 3088875 (1963-05-01), Fisk
patent: 3853987 (1974-12-01), Dreyer
patent: 4105598 (1978-08-01), Yen et al.
patent: 4223005 (1980-09-01), Teodorescu et al.
patent: 4254096 (1981-03-01), Monthony et al.
patent: 4284412 (1981-08-01), Hansen et al.
patent: 4361549 (1982-11-01), Kung et al.
patent: 4361550 (1982-11-01), Kung et al.
patent: 4363799 (1982-12-01), Kung et al.
patent: 4364932 (1982-12-01), Kung et al.
patent: 4364937 (1982-12-01), Kung et al.
patent: 4381295 (1983-04-01), Kung et al.
patent: 4419444 (1983-12-01), Quash
Mirro et al., J. Immunol. Methods, 47, 39-48, (1981).
Parish et al., J. Immunol. Methods, 53: 367-372, (1982).
Sevier et al., Clin. Chem., 27(6), 1109, Jun. (1981).
Identifying Human Lymphocyte Subpopulations and Assaying of Human Neutrophil Function (Reprints from Bio-Rad Laboratories).
The First Lymphochrome.TM. B-Lymphocyte Test (Sigma Chemical Corp., 1 pg. brochure), (1980).
T & B Lymphocyte Identification with Monoclonal Antibodies-Hybritech T & B Cell Reagent Set from Hybritech Inc., (1981), (4 pgs.).
Kallestad Laboratories, Inc.-Kallestand Announces Development of Cellular Immunology Kits (2 pg. article).
Hudson and Hay-"Practical Immunology" Blackwell Scientific Publications, Second Edition.
Sigma Technical Bulletin #95, "An Immunoenzymatic Technic for Detecting Surface Immunoglobulins of Mature B-Lymphocytes, (Nov. 1980).

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