Simulated in vivo measurement of skin characteristics

Details Simulated in vivo measurement of skin characteristics Simulated in vivo measurement of skin characteristics

1988-03-22

1989-06-06

Levy, Stewart J.

Measuring and testing

Moisture content or absorption characteristic of material

By desiccation or extraction

G01N 504

Patent

active

048360147

ABSTRACT:
A method and apparatus for conducting various experiments on skin samples under simulated in vivo conditions. The apparatus includes, in one embodiment, a platform for supporting the skin sample over a chamber containing liquid at a controlled temperature. An activating probe is attached to the surface of the skin sample and is activated in a predetermined manner. The probe is also used to measure the resulting deformations of the skin sample to determine the visco-elastic properties of the skin under various temperature and humidity conditions. The apparatus also includes an access part for applying selected topical solutions to the skin sample. In another embodiment, the apparatus includes additional elements for enclosing the air space above a skin sample and for measuring the transepidermal water loss through the sample.

REFERENCES:
patent: 4050995 (1977-09-01), Bredeweg
patent: 4297884 (1981-11-01), Leveque et al.
patent: 4682608 (1987-07-01), DeRigal et al.
patent: 4711244 (1987-12-01), Kuzara

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