Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1997-04-28
2000-05-30
Shippen, Michael L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
435106, C07C22900
Patent
active
060692723
ABSTRACT:
The invention relates to a three-step synthesis of vinyl glycine (1) using a cheap, commercially available starting material (3-butenenitrile (2)) and using cheap, simple reagents. Also disclosed is a convenient optical resolution of the N-tert.butyloxycarbonyl derivative by papain-catalyzed enantioselective esterification in a two-phase system.
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Crout David Herbert George
Hallinan Keith Oliver
Hoechst Aktiengesellschaft
Shippen Michael L.
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