Simethicone/anhydrous calcium phosphate compositions

Details Simethicone/anhydrous calcium phosphate compositions Simethicone/anhydrous calcium phosphate compositions

1997-07-17

2000-08-15

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424435, 424441, 424451, 424456, 424464, 424465, 424489, 424490, 514770, 514781, 514951, A61K 916, A61K 920, A61K 948, A61K 950

Patent

active

061032603

ABSTRACT:
The invention relates to antifoam oral solid dosage form preparations formed from a free flowing granular composition comprising an admixture of simethicone and either one or both of granular anhydrous tribasic calcium phosphate or dibasic calcium phosphate wherein the admixture is a uniform granular composition of not more than 1000 micron particle size which is suitable for compression into a solid dosage form for oral administration.

REFERENCES:
patent: 4127650 (1978-11-01), Buehler
patent: 4396604 (1983-08-01), Mitra
patent: 4557916 (1985-12-01), Withiam
patent: 4906478 (1990-03-01), Valentine et al.
patent: 5073384 (1991-12-01), Valentine et al.
patent: 5275822 (1994-01-01), Valentine et al.
patent: 5458886 (1995-10-01), Briquet
patent: 5599577 (1997-02-01), Stevens et al.
European Search Report Application No. 98305696 dated Oct. 22, 1998.

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