Silver-based antimicrobial compositions

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Biocides; animal or insect repellents or attractants

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424618, 514152, 514179, 514192, 514199, 514535, A01N 2500, A61K 3338, A61K 3165, A61K 3156

Patent

active

06093414&

ABSTRACT:
The present invention relates generally to silver-based antimicrobial compositions and processes for making such compositions. More particularly, the present invention describes stable, purified silver-based antimicrobial compositions, and processes for making such compositions, comprising carrier-free silver thiosulfate ion complexes either suspended in a base or incorporated into a matrix. These silver thiosulfate ion complex antimicrobial compositions are useful in the treatment and prevention of infections and diseases.

REFERENCES:
patent: 3761590 (1973-09-01), Fox
patent: 5326567 (1994-07-01), Capelli
patent: 5429819 (1995-07-01), Oka et al.
patent: 5651978 (1997-07-01), Tomioka et al.
patent: 5662913 (1997-09-01), Capelli
patent: 5744151 (1998-04-01), Capelli
Tomioka et al., "Synthesis of Antimicrobial Agent Composed of Silver-Thiosulfate Complex Ion," Nippon Kagaku Kaishi 10:848-50 (1995).
Russell et al., Antimicrobial Activity and Action of Silver, Progress in Medicinal Chemistry 31:351-70 (1994).
Dooly et al., "Multidrug-resistant tuberculosis," Ann. Int. Med. 117:257-59 (1992).
Nadler, "Multidrug resistant tuberculosis," N. Eng. J. Med. 327:1172-75 (1992).

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