Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Reexamination Certificate
2004-01-07
2010-11-30
Weber, Jon P (Department: 1657)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
C252S001000, C435S402000, C435S404000, C514S012200
Reexamination Certificate
active
07842780
ABSTRACT:
The present invention provides processes for producing porous silk fibroin scaffold material. The porous silk fibroin scaffold can be used for tissue engineering. The porosity of the silk fibroin scaffolds described herein can be adjusted as to mimic the gradient of densities found in natural tissue. Accordingly, methods for engineering of 3-dimensional tissue, e.g. bone and cartilage, using the silk fibroin scaffold material are also provided.
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Kaplan David L.
Meinel Lorenz
Nazarov Rina
Vunjak-Novakovic Gordana
Massachusetts Institute of Technology
Nixon & Peabody LLP
Srivastava Kailash C
Trustees of Tufts College
Weber Jon P
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