Silicone-hardened pharmaceutical microcapsules

Plastic and nonmetallic article shaping or treating: processes – Encapsulating normally liquid material – Liquid encapsulation utilizing an emulsion or dispersion to...

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264 46, 42721332, 42721336, 514963, 424460, A61K 950

Patent

active

051436612

ABSTRACT:
There is disclosed a process for preparing compositions comprising microcapsules by phase separation microencapsulation wherein the hardening agent employed is a volatile silicone fluid and with the compositions prepared thereby. The use of the volatile silicone fluid as a hardening agent permits the production of microcapsules substantially free of any alkane hardening agent, eliminating potential combustability problems of the prior art processes and toxicity problems of the prior art compositions.

REFERENCES:
patent: 4107071 (1978-08-01), Bayless
patent: 4675189 (1987-06-01), Kent et al.
patent: 4685883 (1987-08-01), Jernberg
patent: 4732763 (1988-03-01), Beck et al.
patent: 4917893 (1990-04-01), Okada et al.
patent: 4935171 (1990-06-01), Bracken
patent: 4954381 (1990-09-01), Cabasso et al.
patent: 5000886 (1991-03-01), Lawter et al.

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