Silica-calcium phosphate bioactive composite for improved...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form

Reexamination Certificate

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C424S600000, C424S601000, C424S682000, C424S724000

Reexamination Certificate

active

11282864

ABSTRACT:
A resorbable silica-calcium phosphate bioactive composite that finds utility for drug delivery. The bioactive composite is loaded with a pharmaceutical composition and releases a therapeutically effective amount of a pharmaceutical composition for periods of up the 28 days.

REFERENCES:
patent: 5082808 (1992-01-01), Nonami et al.
patent: 5968253 (1999-10-01), Poser et al.
patent: 6511510 (2003-01-01), de Bruijn et al.
patent: WO 97/40137 (1997-10-01), None
Knabe et al., “Morphological evaluation of osteoblasts cultured on different calcium phosphate ceramics”, Biomaterials, 1997, pp. 1339-1347, vol. 18, Elssevier Science Limited, Great Britain.

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